Elbonix

Eltrombopag Olamine (Elbonix) is a small molecule thrombopoietin (TPO) receptor agonist. Eltrombopag interacts with the transmembrane domain of the human TPO-receptor and initiates signaling cascades that induce proliferation and differentiation from bone marrow progenitor cells finally leading to increased platelet production.

Eltrombopag tablet is indicated for treatment of thrombocytopenia in patients with persistent or chronic immune thrombocytopenia. It is also indicated for treatment of thrombocytopenia in patients with hepatitis C infection and severe aplastic anemia.

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